An Improvement Over the CODA Filterfor LC-MS Analysis
نویسندگان
چکیده
Liquid chromatography combined with mass spectrometry (LC-MS) analysis has been successfully employed in proteome research. Data generated from LC-MS equipments usually comes with a considerable amount of noise. Thus, there is a need for the use of filters to enhance the quality of mass spectrometry chromatograms. An algorithm developed recently (CODA[2]) achieves good results in removing noise in a short time. On the present work it will be shown some modifications to the CODA algorithm that improve considerably its results. Further, a set of testing chromatograms will be presented to demonstrate the efficiency of the modified algorithm.
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